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Tumor-Induced Immune Suppression

Mechanisms and Therapeutic Reversal

By Dmitry I. Gabrilovich

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Publish Date

2014

Publisher

Springer London, Limited

Language

eng

Pages

388

Description:

This book presents a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance.