Translational and experimental clinical research

Description:

This volume is a comprehensive textbook for investigators entering the rapidly growing field of translational and experimental clinical research. The book offers detailed guidelines for designing and conducting a study and analyzing and reporting results and discusses key ethical and regulatory issues. Chapters address specific types of studies such as clinical experiments in small numbers of patients, pharmacokinetics and pharmacodynamics, and gene therapy and pharmacogenomic studies. A major section describes modern techniques of translational clinical research, including gene expression, identifying mutations and polymorphisms, cloning, transcriptional profiling, proteomics, cell and tissue imaging, tissue banking, evaluating substrate metabolism, and in vivo imaging.

subjects: Statistical methods,  Research Design,  Clinical trials,  Statistical Data Interpretation,  Research,  Methodology,  Methods,  Medicine,  Biomedical Research,  Medical research,  Internal Medicine,  Medical,  Medical / Nursing,  Epidemiology,  Medical / Research,  Research Design .,  Medisch onderzoek,  Onderzoeksmethoden,  Experimenteel onderzoek,  Medecine,  Recherche,  Methodologie,  Methodes statistiques,  Etudes cliniques,  Medicine, experimental,  Clinical Trials as Topic