The impact of stereochemistry on drug development and use

Description:

The book explores analytical, pharmacological, and regulatory topics in dealing with the theory and practice of stereochemistry in the pharmarceutical industry today. This exciting, broad-appeal treatment extends from the analytical viewpoint in enantiomeric separation to the regulatory issues involved in the "racemate-versus-enantiomer" debate. The authors include numerous examples and case studies, and integrate material from a wide range of studies, publications, and workshops. The Impact of Stereochemistry on Drug Development and Use is an essential reference for medicinal and analytical chemists, pharmacologists, drug metabolism and pharmacokinetic scientists, and personnel of regulatory agencies. It is also a useful text for graduate students in stereochemistry, and for anyone who wants to keep up with the swift pace of change in this dynamic field.

subjects: Arzneimittel,  Emploi en therapeutique,  Chiralite,  Chiral drugs,  Stereochimie,  Pharmaceutical Chemistry,  Chimie analytique,  Medicaments,  Stereoisomerism,  Enantiomeres,  Molecular Conformation,  Synthese,  Stereoisomerie,  Separation,  Struktur-Aktivita˜ts-Beziehung,  Stereochemie,  Medicaments chiraux,  Methods,  Drugs, research,  Stereochemistry