Chemical Biology

Description:

"The present selection of 12 experiments has been carefully selected to cover the most commonly used laboratory techniques for the synthesis and analysis of bioactive compounds. Together, they provide a solid introduction to the skills and techniques that are required for the successful study of Chemical Biology." "Here you will learn how to: synthesize a peptide by solid phase synthesis; modify a protein by covalent attachment of a lipid chain; modify an oligonucleotide and use it for DNA-directed immobilization; isolate an enzyme for in vitro synthesis of a polysaccharide; design a ligand for a protein by molecular modeling; and perform a proteome analysis in yeast." "All experiments haven been thoroughly tested in the authors' laboratory and come with an easy to follow step-by-step instruction, complemented by abundant practical hints and by a thorough treatment of the underlying theory and mechanisms."--Jacket.

subjects: Combinatorial chemistry,  Bioactive compounds,  Synthesis,  Chimie combinatoire,  Manuels de laboratoire,  Biochemie,  Bioorganic chemistry