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The chaperonopathies

The chaperonopathies

diseases with defective molecular chaperones : an introduction and guide to diseases in which chaperones play an etiologic-pathogenic role

By Alberto J. L. Macario

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Publish Date

2013

Publisher

Springer

Language

eng

Pages

116

Description:

This Brief provides a concise review of chaperonopathies, i.e., diseases in which molecular chaperones play an etiologic-pathogenic role. Introductory chapters deal with the chaperoning system and chaperoning teams and networks, HSP-chaperone subpopulations, the locations and functions of chaperones, and chaperone genes in humans. Other chapters present the chaperonopathies in general, including their molecular features and mechanistic classification into by defect, excess, or mistake. Subsequent chapters discuss the chaperonopathies in more detail, focusing on their distinctive characteristic.