Genomics of pattern recognition receptors

Description:

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.--

subjects: Cell receptors,  Genetics,  Genomic Structural Variation,  Pattern Recognition Receptors,  Cardiovascular Diseases,  Neoplasms,  Genetik,  Kardiovaskuläre Krankheit,  Genomik,  Humangenetik,  Onkologie,  Immunology,  Cancer, research,  Human genetics