Microarrays for an integrative genomics

Description:

Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.

subjects: Automation,  Bioinformatics,  DNA microarrays,  Genomics,  Microarray,  Data Mining,  Gene expression,  Genanalyse,  Puces à ADN,  Computational Biology,  Genetics & Genomics,  SCIENCE,  Life Sciences,  Oligonucleotide Array Sequence Analysis,  Gene expression profiling,  Bio-informatique,  Automatisation,  Methods,  Génomique,  Scientific computing,  Genetics - dna & rna,  Genetics,  Genetics - general and miscellaneous,  Biology - biotechnology